| Autor: |
Oxman, Michael N., Levine, Arthur S., Crumpacker, Clyde S., Levin, Myron J., Henry, Patrick H., Lewis, Andrew M. |
| Zdroj: |
The Journal of Virology; August 1971, Vol. 8 Issue: 2 p215-224, 10p |
| Abstrakt: |
Ad2+ND1, a nondefective adenovirus 2 (Ad2)-simian virus 40 (SV40) hybrid virus, has been previously shown to contain a small segment of the SV40 genome covalently linked to Ad2 deoxyribonucleic acid (DNA). The SV40 portion of this hybrid virus has been characterized by relating the SV40-specific ribonucleic acid (RNA) sequences transcribed from the Ad2+ND1DNA to those transcribed from the DNA of SV40 itself. RNA-DNA hybridization-competition studies indicate that the SV40 component of Ad2+ND1consists of some, but not all, of that part of the SV40 genome which is transcribed early, i.e., prior to viral DNA replication, in SV40 lytic infection. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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