| Autor: |
Altstein, A. D., Dodonova, N. N., Vassilyeva, N. N., Tsetlin, E. M. |
| Zdroj: |
The Journal of Virology; May 1968, Vol. 2 Issue: 5 p488-493, 6p |
| Abstrakt: |
Following joint replication of monkey SA7 adenovirus (C8 strain) and human adenovirus type 2 in green monkey kidney tissue culture, a virus possessing the properties of a hybrid was obtained. It was designated Ad2C8. Ad2C8 preparations contained two types of viral particles: human adenovirus type 2, and hybrid particles. The hybrid virions multiplied in green monkey kidney cells in the presence of human adenovirus types 1, 2, and 3, but not 3 and 7, and acquired the capsid of the helper adenovirus. The hybrid can serve as a helper for human adenoviruses. It can apparently induce T antigen of the C8 virus but, in contrast to the latter, does not induce tumors in hamsters. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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