Mechanism of action involved in the anxiolytic-like effects of Hibalactone isolated from Hydrocotyle umbellataL.

Autor: Gabriel de Oliveira, Matheus, Kelle da Silva Moreira, Lorrane, Turones, Larissa Cordova, de Souza Almeida, Dionys, Martins, Aline Nazareth, Silva Oliveira, Thiago Levi, Barreto da Silva, Vinicius, Borges, Leonardo Luiz, Costa, Elson Alves, Realino de Paula, José
Zdroj: Journal of Traditional and Complementary Medicine; 20210101, Issue: Preprints
Abstrakt: Hibalactone (HB) is a lignan related to the anxiolytic-like effects of Hydrocotyle umbellataL. However, there is a need to understand better the mechanism of action of this lignan to support the ethnopharmacological uses of the species. This work aimed to evaluate by in vivoand in silicoanalysis the mechanism of action of HB involved in its anxiolytic-like effects.
Databáze: Supplemental Index