| Autor: |
Madsen, R D, Saeed, F A, Gray, O, Fendly, B M, Coates, S R |
| Zdroj: |
Journal of Clinical Microbiology; October 1986, Vol. 24 Issue: 4 p680-683, 4p |
| Abstrakt: |
A murine immunoglobulin G1 monoclonal antibody was produced that binds to a protease-sensitive, periodate-insensitive epitope on a 43,000-molecular-weight Mycoplasma pneumoniae membrane polypeptide. The 43,000-molecular-weight polypeptide appeared to be a major antigenic component of M. pneumoniae, as determined by immunoblot analysis. This monoclonal antibody reacted with 33 different clinical isolates of M. pneumoniae, but not with normal-flora Mycoplasma species or 18 other microorganisms potentially inhabiting the normal or diseased human respiratory tract. This apparent species-specific monoclonal antibody may have application for the detection of M. pneumoniae antigen in clinical specimens. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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