Identity of the photoproduct that causes lacI mutations in UV-irradiated Escherichia coli

Autor: Lawrence, C W, Christensen, R B, Christensen, J R
Zdroj: Journal of Bacteriology; February 1985, Vol. 161 Issue: 2 p767-768, 2p
Abstrakt: Estimates of the capacity of photoreactivation to act specifically on premutational lesions were obtained by conjugational transfer of an F' lac plasmid from a UV-irradiated, photoreactivated donor to a delta (pro-lac) recipient that had been UV irradiated and allowed to induce SOS functions for 30 min. This treatment reduced the frequency of induced lacI mutations by 70 to 80%, indicating that cyclobutane dimers cause most mutations in this system.
Databáze: Supplemental Index