Acquisitive evolution of ribitol dehydrogenase in Klebsiella pneumoniae

Autor: Thompson, L W, Krawiec, S
Zdroj: Journal of Bacteriology; May 1983, Vol. 154 Issue: 2 p1027-1031, 5p
Abstrakt: Selection in continuous culture of Klebsiella pneumoniae mutants that have gained the ability to utilize xylitol while also retaining regulatory control over ribitol utilization was achieved with a dual-substrate regime. Initial steady-state cultures of wild-type organisms were maintained with 0.005% (0.329 mM) ribitol. Mutants of various types proliferated when the composition of the limiting medium was changed to 0.005% ribitol plus 0.250% (16.43 mM) xylitol.
Databáze: Supplemental Index