Phospholipid Metabolism During Penicillinase Production in Bacillus licheniformis

Autor: Morman, Manuel R., White, David C.
Zdroj: Journal of Bacteriology; October 1970, Vol. 104 Issue: 1 p247-253, 7p
Abstrakt: During membrane-bound penicillinase production, Bacillus licheniformisforms vesicles and tubules that do not appear in the absence of penicillinase production. The major lipids of B. licheniformiswere shown to be phospholipids. The proportions, metabolism, and the total phospholipid per cell were shown to be essentially the same in the uninduced control, induced and constitutive penicillinase forming cells during both the exponential and stationary growth phases. Membrane phospholipids were not secreted into the medium during penicillinase formation. In the shift from the exponential to the stationary growth phase, there was an accumulation of phosphatidyl glycerol and a marked decrease in cardiolipin. These two lipids had the most active turnover of their phospholipid phosphate of all the lipids studied.
Databáze: Supplemental Index