| Autor: |
Gordon, Julian, Schweiger, Manfred, Krisko, Istvan, Williams, Curtis A. |
| Zdroj: |
Journal of Bacteriology; October 1969, Vol. 100 Issue: 1 p1-4, 4p |
| Abstrakt: |
Antisera have been prepared against two electrophoretically homogeneous “polypeptide chain elongation factors,” T and G, from Escherichia coli. Inactivation and precipitation tests showed that these two fractions were antigenically distinct with no cross-reaction. The immune inactivation curve of G factor from E. coliwas distinguishable from that of G factor from Pseudomonas fluorescens. Mammalian factors were not inhibited by antibody directed against the E. coliT and G factors. By Ouchterlony diffusion tests, the antisera also detected significant antigenic variability among different bacterial species. It is concluded that the factors have undergone considerable evolutionary divergence in their antigenic structure. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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