Induction of SAP7Correlates with Virulence in an Intravenous Infection Model of Candidiasis but Not in a Vaginal Infection Model in Mice

Autor: Taylor, Brad N., Hannemann, Holger, Sehnal, Miriam, Biesemeier, Antje, Schweizer, Anja, Röllinghoff, Martin, Schröppel, Klaus
Zdroj: Infection and Immunity; October 2005, Vol. 73 Issue: 10 p7061-7063, 3p
Abstrakt: ABSTRACTSAP7of Candida albicansis induced after vaginal infection of mice. Conversely, virulence during vaginal infection was not affected in a Δsap7/Δsap7mutant strain. Only a partial virulence phenotype was detectable after intravenous injection. In conclusion, SAP7expression does not correlate with C. albicansvirulence in mice.
Databáze: Supplemental Index