Complement Receptor 3 Binds the Borrelia burgdorferiOuter Surface Proteins OspA and OspB in an iC3b-Independent Manner

Autor: Garcia, Rodolfo C., Murgia, Rossella, Cinco, Marina
Zdroj: Infection and Immunity; September 2005, Vol. 73 Issue: 9 p6138-6142, 5p
Abstrakt: ABSTRACTPersistence of borreliae within the vertebrate host depends on the fate of interactions between the spirochetes and target cells. The present work demonstrates the direct binding of the Borrelia burgdorferiouter surface proteins OspA and OspB to CR3 and that this binding is independent of iC3b.
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