| Autor: |
Dunn, Kate L. R., Farrant, Jayne L., Langford, Paul R., Kroll, J. Simon |
| Zdroj: |
Infection and Immunity; March 2003, Vol. 71 Issue: 3 p1604-1607, 4p |
| Abstrakt: |
ABSTRACTSuperoxide dismutase cofactored by copper and zinc ([Cu,Zn]-SOD) contributes to the protection of opsonized serogroup B Neisseria meningitidisagainst phagocytosis by human monocytes/macrophages, with sodCmutant organisms being endocytosed in significantly higher numbers than are wild-type organisms. The influence of [Cu,Zn]-SOD was found to be exerted at the stage of phagocytosis, rather than at earlier (modulating surface association) or later (intracellular killing) stages. |
| Databáze: |
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