| Autor: |
Nachamkin, Irving, Liu, Jirong, Li, Ming, Ung, Huong, Moran, Anthony P., Prendergast, Martina M., Sheikh, Kazim |
| Zdroj: |
Infection and Immunity; September 2002, Vol. 70 Issue: 9 p5299-5303, 5p |
| Abstrakt: |
ABSTRACTGM1- and GD1a-like ganglioside mimicry in Campylobacter jejunilipooligosaccharide (LOS) is considered to be involved in the pathogenesis of Campylobacter-induced Guillain-Barré syndrome (GBS). Compared with gastroenteritis-related isolates, GBS-related C. jejuniisolates were strongly associated with the expression of GD1a-like mimicry. The presence of a few genes involved in LOS ganglioside mimicry, cst-II, cgtA, and cgtB, was also associated with GBS-related strains. GD1a-like epitope expression may be an important virulence phenotype associated with the risk of developing GBS following campylobacter infection. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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