| Autor: |
Roach, D. R., Briscoe, H., Baumgart, K., Rathjen, D. A., Britton, W. J. |
| Zdroj: |
Infection and Immunity; October 1999, Vol. 67 Issue: 10 p5473-5476, 4p |
| Abstrakt: |
ABSTRACTTumor necrosis factor (TNF) is a critical mediator in the immune response to mycobacteria, particularly in the formation and maintenance of granulomas. Treatment of Mycobacterium bovisBCG-infected mice with TNF and a TNF-mimetic peptide (TNF70–80) altered the number and cellular composition of granulomas. This change was associated with a moderate decrease in the bacterial burden. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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