Autor: |
Nicholas, R. O., Li, Tong, McDevitt, D., Marra, Andrea, Sucoloski, S., Demarsh, P. L., Gentry, D. R. |
Zdroj: |
Infection and Immunity; July 1999, Vol. 67 Issue: 7 p3667-3669, 3p |
Abstrakt: |
ABSTRACTThe sigBgene of Staphylococcus aureus, coding for the alternate sigma factor B, has been deleted by allelic replacement mutagenesis. The mutant grew as well as the parent in vitro, although it was deficient in clumping factor, coagulase, and pigment. In two murine and one rat infection model the mutant showed no reduction in virulence. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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