| Abstrakt: |
Our research work focussed on to evaluating the synergistic action of ethanolic extract and its formulations (F1 and F2) of Cinnamomum zeylanicum(ECZ) and Murraya koenigii(EMK) for antiobesity and anti-hyperlipidemic activity on the high-fat diet on wistar albino rats. In this research work, rats fed on high-fat diet produced hyperlipidemia (115.00 ± 1.36 mg/dL), which led to an gain in the body weight (215 g), the total cholesterol, triglycerides (166.0 ± 0.577 mg/dL), VLDL (33.20 ± 0.233 mg/dL), total bilirubin (3.280 ± 0.010 mg/dL) and subside the levels of HDL (41.0 ± 0.894 mg/dL) and also changes in albino rats body temperature. ECZ, EMK, and its formulation F1, F2 (200 mg/kg and 400 mg/kg) indicated less in comparison to the HFD induced rats group. The result of the study reflected that ECZ, EMK, and its formulation F1, F2 showed antiobesity and anti-hyperlipidemic action depending on the dose. It was concluded that the ethanolic extract of C. zeylanicum, M. koenigiiand its formulation F1, F2 possess antiobesity and anti-hyperlipidemic activity. It is drawn to conclusions, alcoholic extract of C. zeylanicumand M. koenigiiand its formulation F1 and F2 possess antiobesity and anti-hyperlipidemic activity. |
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