Distribution of glucose incorporated into macromolecular material by treponema pallidum

Autor: Barbieri, J T, Austin, F E, Cox, C D
Zdroj: Infection and Immunity; March 1981, Vol. 31 Issue: 3 p1071-1077, 7p
Abstrakt: Treponema pallidum was observed to incorporate glucose carbons into lipids, ribonucleic acid, deoxyribonucleic acid, and protein. Only the glycerol portions of phosphatidylcholine and phosphatidylglycerol contained glucose-derived carbons. Incorporation of exogenous choline into phosphatidylcholine was detected. Glucose was incorporated into only the pentoses of nucleic acids. About 50% of the glucose incorporated into protein was present in only one amino acid, aspartate. Evidence suggests that aspartate synthesis could follow the conversion of phosphoenolpyruvate to oxalacetic acid by a guanosine 5'-diphosphate-dependent phosphoenolpyruvate carboxykinase.
Databáze: Supplemental Index