| Autor: |
Wheat, R W, Su Chung, K S, Ornellas, E P, Scheer, E R |
| Zdroj: |
Infection and Immunity; January 1978, Vol. 19 Issue: 1 p152-159, 8p |
| Abstrakt: |
Water, perchloric acid extracts, and fractions of partially defatted whole mycelia of Coccidioides immitis contained delayed skin test activity when tested in C. immitis-infected guinea pits. Aqueous phenol extraction of these fractions resulted in partitioning of activity between aqueous-soluble and phenol-soluble fractions; activity was found to be water soluble after removal of phenol by extensive dialysis. Highest specific activity skin test antigen was invariably found in the phenol-soluble phase, water-soluble fraction. Material of equivalent activity could also be extracted directly from the defatted mycelia. Skin test active fractions contained glucose, mannose, 3-O-methylmannose, glucosamine, and amino acids. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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