| Autor: |
Berquist, K R, Peterson, J M, Murphy, B L, Ebert, J W, Maynard, J E, Purcell, R H |
| Zdroj: |
Infection and Immunity; September 1975, Vol. 12 Issue: 3 p602-605, 4p |
| Abstrakt: |
We report the temporal patterns of various immunohistological and serological parameters of acute self-limited hepatitis B virus infection of two chimpanzees, and we provide evidence that the synthesis of hepatitis B core antigen precedes that of hepatitis B surface antigen. Our data suggest that existence of a biphasic hepatitis B virus infection involving a hematogenous reinfection of the liver and indicate that recruitment of liver cells to produce hepatitis B virus may occur in a pattern consistent with a replicative cycle of about 8 days. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
