| Autor: |
Rocha-Rodrigues, Denise Bertulucci, Paschoini, Giovana, Pereira, Sanivia Aparecida Lima, Reis, Marlene Antonia dos, Teixeira, Vicente de Paula Antunes, Rodrigues, Virmondes |
| Zdroj: |
Clinical and Vaccine Immunology (formerly CDLI); September 2003, Vol. 10 Issue: 5 p741-743, 3p |
| Abstrakt: |
ABSTRACTEndemic pemphigus foliaceus (EPF) is an autoimmune disease characterized by blister formation with a loss of cohesion and infiltration of inflammatory cells. We observed that supernatants of peripheral blood mononuclear cells from patients produced significantly more interleukin-1ß (IL-1ß) than those from stimulated healthy controls. Furthermore, a Th2 bias was observed in EPF patients when the IL-5/gamma interferon ratio was analyzed. These results indicate that cells from pemphigus patients react with a vigorous proinflammatory response. |
| Databáze: |
Supplemental Index |
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