Autor: |
Goodman, Joseph J., Smith, Leland L. |
Zdroj: |
Applied Microbiology; September 1961, Vol. 9 Issue: 5 p372-375, 4p |
Abstrakt: |
9α-Fluorohydrocortisone is hydroxylated by Streptomyces roseochromogenesin the 16α-, the 2β-, and in both the 16α- and 2β- positions. 16α-Hydroxylation appears to be the more predominant and rapid pathway of transformation. The degree of 2β-hydroxylation is dependent upon the strain used and may be increased to the point of its being a major route or virtually eliminated by the proper selection of isolates. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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