| Autor: |
Teuscher, C, Yanagihara, D, Brennan, P J, Koster, F T, Tung, K S |
| Zdroj: |
Infection and Immunity; May 1985, Vol. 48 Issue: 2 p474-479, 6p |
| Abstrakt: |
The level of circulating antibody to phenolic glycolipid I of Mycobacterium leprae was determined in 18 inbred strains of mice after immunization with M. leprae organisms. By using a solid-phase radioimmunoassay with phenolic glycolipid I as test antigen, a continuous distribution of antibody levels ranging from high to low was observed. The level was found to be controlled by multiple genes, including both H-2 complex- and Igh allotype complex-linked genes. Low antibody response to phenolic glycolipid I was shown to be inherited as a dominant trait in three combinations of high X low responder F1 progeny. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
