Absorption of carbonyl iron

Autor: Huebers, H.A., Brittenham, G.M., Csiba, E., Finch, C.A.
Zdroj: Journal of Laboratory and Clinical Medicine; November 1986, Vol. 108 Issue: 5 p473-478, 6p
Abstrakt: The mechanism of carbonyl iron absorption has been studied in rats. Solubilization by gastric acid was a prerequisite for subsequent absorption. The slow rate of solubilization resulted in a more prolonged absorption, responsible for the low toxicity of carbonyl iron. Large doses of carbonyl iron were held for several days by the gastric mucosa of iron-deficient animals. Once it had been solubilized, the subsequent pathway of absorption by the intestinal mucosa and the amount absorbed was similar to that of ferrous ammonium sulfate.
Databáze: Supplemental Index