| Autor: |
Comunidad-Bonilla, Roque A, Navarro-Gerrard, Megan A, Uribe-Uribe, Norma, Ramírez-Andrade, Silvia E, Cohen-Bucay, Abraham, Mejia-Vilet, Juan M |
| Zdroj: |
Journal of Onco-Nephrology; June 2021, Vol. 5 Issue: 2 p140-144, 5p |
| Abstrakt: |
Crystalcryoglobulinemia refers to the extracellular deposition of crystals in the systemic vasculature, leading to vascular injury, thrombosis, and occlusion. This entity is usually described as a complication of multiple myeloma, although it can also occur in the setting of a monoclonal gammopathy of renal significance. Synchronous presentation of a monoclonal gammopathy and renal cell carcinoma is rare. Hypothetically, as both neoplasms’ growth depends on certain cytokines such as interleukin-6, it is possible that cytokine production from one neoplasm may stimulate the growth of the other. In this report, we describe a case of crystalcryoglobulinemia in a patient with a monoclonal gammopathy of renal significance and concomitant renal cell carcinoma. Additionally, we performed a systematic review of the literature and analyzed data of 61 reported cases of crystalcryoglobulinemia and of 40 reported cases describing the association between multiple myeloma and renal cell carcinoma. |
| Databáze: |
Supplemental Index |
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