| Autor: |
Frantz, D. E., Morency, L., Soheili, A., Murry, J. A., Grabowski, E. J. J., Tillyer, R. D. |
| Zdroj: |
Organic Letters; March 2004, Vol. 6 Issue: 5 p843-846, 4p |
| Abstrakt: |
A one-pot synthesis of substituted imidazoles is described. The cornerstone of this methodology involves the thiazolium-catalyzed addition of an aldehyde to an acyl imine to generate the corresponding α-ketoamide in situ followed by ring closure to the imidazole in a one-pot sequence. The extension of this methodology to the one-pot synthesis of substituted oxazoles and thiazoles is also described. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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