Autor: |
Lozzio, B B, Machado, E A, Lozzio, C B, Lair, S |
Zdroj: |
The Journal of Experimental Medicine; January 1976, Vol. 143 Issue: 1 p225-231, 7p |
Abstrakt: |
A new animal model characterized by hereditary athymia and asplenia was used as a recipient of chronic myelogenous leukemic (CML) cells with the Philadelphia (Ph1+) chromosome. Transplanted CML cells form solid vascularized tumors containing cells similar to those seen in the patient in a long-term culture. Cells taken from the tumors were nearly triploid, retained all human chromosome markers, and had the same antigenic determinants(s) as cells in culture. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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