| Autor: |
Rabinowe, S L, Nayak, R C, Krisch, K, George, K L, Eisenbarth, G S |
| Zdroj: |
The Journal of Experimental Medicine; May 1987, Vol. 165 Issue: 5 p1436-1441, 6p |
| Abstrakt: |
A new human T cell subset defined by antineuronal ganglioside mAb 3G5 increases linearly with advancing age in man. The percentage of circulating 3G5+ T cells in 21 normal individuals, quantitated by cytofluorograph analysis, increases linearly from age 7 (23-30%) to age 84 (58%) (r = 0.85, p less than 0.001). The antigen on T cells has the biochemical properties of a ganglioside that migrates between GM1 and GM2 ganglioside markers on TLC. The 3G5 subset represents the first T cell subset that reflects aging in man. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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