Complement receptor mediates enhanced flavivirus replication in macrophages.

Autor: Cardosa, M J, Porterfield, J S, Gordon, S
Zdroj: The Journal of Experimental Medicine; July 1983, Vol. 158 Issue: 1 p258-263, 6p
Abstrakt: Evidence is presented that M phi complement receptors (CR3) mediate IgM-dependent enhancement of flavivirus replication in the presence of complement. Enhancement is blocked by pretreatment of macrophages with monoclonal antibody Ml/70, which inhibits CR3 binding, but not by pretreatment with monoclonal antibody 2.4G2, which inhibits FcR binding.
Databáze: Supplemental Index