Autor: |
Lattime, E C, Pecoraro, G A, Stutman, O |
Zdroj: |
The Journal of Experimental Medicine; March 1983, Vol. 157 Issue: 3 p1070-1075, 6p |
Abstrakt: |
Murine natural killer (NK) and natural cytotoxic (NC) cells showed different patterns of augmentation of lytic activity after preincubation for 24 h with either poly-IC, interleukin 2 (IL-2), or interleukin 3 (IL-3): (a) Poly-IC augmented only NK cells, with no effect on NC activity, as we have previously observed (4); (b) IL-2 augmented both NK and NC activity; and (c) IL-3 augmented only NC lysis, without affecting NK activity. In addition, both precursor and the augmented effector cells showed differences in expression of the Qa-5 surface marker: NK precursors and effectors are Qa 5+, whereas NC precursors and effector cells are Qa-5-. |
Databáze: |
Supplemental Index |
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