| Autor: |
Lage, Luis Alberto de Padua Covas, Brito, Claudio Vinicius, Levy, Debora, Culler, Hebert Fabricio, Couto, Samuel Campanelli Freitas, Alves, Lucas BO, Zerbini, Maria C, Rocha, Vanderson, Pereira, Juliana |
| Zdroj: |
Blood; November 2020, Vol. 136 Issue: 1, Number 1 Supplement 1 p38-38, 1p |
| Abstrakt: |
Introduction: Nodal peripheral T-cell lymphomas (nPTCLs) comprise a heterogeneous group of mature and aggressive T-cell lymphoid malignancies, including peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS), angioimmunoblastic T-cell lymphoma (AITL) and anaplastic large cell lymphomas (ALCL) ALK1-positive and ALK1-negative. The differential diagnosis of nPTCL can be very challenging in clinical practice and it has a markedly heterogeneous prognosis. Accurate biomarkers to distinguish the different histological subtypes of nPTCL and to stratify its prognosis are essential to improve the therapeutic approach. The aim of this study was to assess the prognostic impact of GATA3gene expression, as well as its ability to discriminate between different histopathological subtypes of nPTCLs. |
| Databáze: |
Supplemental Index |
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