| Autor: |
Xu, Sixue, Deng, Yupian, He, Jingjing, Zeng, Qianding, Liu, Chuan, Zhang, Yi, Zhu, Bin, Cao, Song |
| Zdroj: |
Organic Letters; August 2021, Vol. 23 Issue: 15 p5853-5858, 6p |
| Abstrakt: |
Four unprecedented base-catalyzed/mediated nucleophilic additions of TMSCN to α-(trifluoromethyl)styrenes and 2-trifluoromethyl enynes were developed. The reaction proceeded smoothly at room temperature under mild and transition-metal-free conditions without affecting the trifluoromethyl group and afforded the corresponding CF3-containing alkyl, alkynyl, and butadienyl nitriles in moderate to excellent yields in a highly regioselective manner, respectively. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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