Recombination and Selection Can Remove blaTEMAlleles from Bacterial Populations

Autor: Mroczkowska, Joanna E., Barlow, Miriam
Zdroj: Antimicrobial Agents and Chemotherapy; September 2008, Vol. 52 Issue: 9 p3408-3410, 3p
Abstrakt: ABSTRACTWe passaged cells expressing TEM-1 and TEM-12 from a single plasmid through either ampicillin or ceftazidime. We found that the combined effects of recombination and selection removed the blaTEM-1allele from the bacterial population when it was passaged through ceftazidime or the blaTEM-12allele when cultures were passaged through ampicillin.
Databáze: Supplemental Index