| Autor: |
Papon, Nicolas, Noël, Thierry, Florent, Martine, Gibot-Leclerc, Stéphanie, Jean, Dorothée, Chastin, Christiane, Villard, Jean, Chapeland-Leclerc, Florence |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; January 2007, Vol. 51 Issue: 1 p369-371, 3p |
| Abstrakt: |
ABSTRACTInactivation of the FCY2(cytosine permease), FCY1(cytosine deaminase), and FUR1(uracil phosphoribosyltransferase) genes in Candida lusitaniaeproduced two patterns of resistance to flucytosine. Mutant fur1demonstrated resistance to 5-fluorouracil, whereas mutants fcy1and fcy2demonstrated fluconazole resistance in the presence of subinhibitory flucytosine concentrations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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