| Autor: |
Tankovic, Jacques, Lascols, Christine, Sculo, Quentin, Petit, Jean-Claude, Soussy, Claude-James |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; December 2003, Vol. 47 Issue: 12 p3942-3944, 3p |
| Abstrakt: |
ABSTRACTIn one French hospital the rate of resistance to ciprofloxacin in Helicobacter pyloriwas 3.3% (2 of 60 strains) in 1999. The six resistant clinical strains (four from 1996 and two from 1999) and three ciprofloxacin-selected single-step mutants studied carried one gyrAmutation but none in gyrB. Clinafloxacin and garenoxacin were the most active fluoroquinolones against these mutants. Occurrence of a second gyrAmutation was associated with high MICs of all fluoroquinolones tested. |
| Databáze: |
Supplemental Index |
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