Antimicrobial Susceptibility and Macrolide Resistance Inducibility of Streptococcus pneumoniaeCarrying erm(A), erm(B), or mef(A)

Autor: Syrogiannopoulos, George A., Grivea, Ioanna N., Ednie, Lois M., Bozdogan, Bülent, Katopodis, George D., Beratis, Nicholas G., Davies, Todd A., Appelbaum, Peter C.
Zdroj: Antimicrobial Agents and Chemotherapy; August 2003, Vol. 47 Issue: 8 p2699-2702, 4p
Abstrakt: ABSTRACTErythromycin-resistant Streptococcus pneumoniaeisolates from young carriers were tested for their antimicrobial susceptibility; additionally, inducibility of macrolide and clindamycin resistance was investigated in pneumococci carrying erm(A), erm(B), or mef(A). Of 125 strains tested, 101 (81%) were multidrug resistant. Different levels of induction were observed with erythromycin, miocamycin, and clindamycin in erm(B) strains; however, in erm(A) strains only erythromycin was an inducer. Induction did not affect macrolide MICs in mef(A) strains.
Databáze: Supplemental Index