Effects of F171 Mutations in the 6′-N-Acetyltransferase Type Ib [AAC(6′)-Ib] Enzyme on Susceptibility to Aminoglycosides

Autor: Chavideh, Ramona, Sholly, Steven, Panaite, Doina, Tolmasky, Marcelo E.
Zdroj: Antimicrobial Agents and Chemotherapy; November 1999, Vol. 43 Issue: 11 p2811-2812, 2p
Abstrakt: ABSTRACTSubstitutions at position F171 of 6′-N-acetyltransferase type Ib cause variable loss of aminoglycoside resistance, indicating that this residue plays an important role in the structure and/or function of the enzyme.
Databáze: Supplemental Index