In vitro activity of cefpodoxime proxetil (U-76,252; CS-807) against Neisseria gonorrhoeae

Autor: Schaadt, R D, Yagi, B H, Zurenko, G E
Zdroj: Antimicrobial Agents and Chemotherapy; February 1990, Vol. 34 Issue: 2 p371-372, 2p
Abstrakt: Cefpodoxime proxetil is an oral cephalosporin antibiotic. The in vitro activities of cefpodoxime (the active metabolite of cefpodoxime proxetil), ceftriaxone, and cefuroxime against both antibiotic-susceptible and antibiotic-resistant clinical isolates of Neisseria gonorrhoeae were determined. Cefpodoxime inhibited all penicillin-susceptible strains and penicillinase-producing strains at less than or equal to 0.015 microgram/ml; chromosomally resistant strains were inhibited by cefpodoxime at less than or equal to 0.125 microgram/ml.
Databáze: Supplemental Index