Production and induction of beta-lactamase during growth of Pseudomonas aeruginosa in biological fluids

Autor: Letendre, E D, Turgeon, P L
Zdroj: Antimicrobial Agents and Chemotherapy; May 1989, Vol. 33 Issue: 5 p776-777, 2p
Abstrakt: beta-Lactamase production in biological fluids was evaluated by using an antibiotic-resistant Pseudomonas aeruginosa strain. Enzyme production was low in plasma or ascitic fluid and high in urine. Induction of beta-lactamase by imipenem was studied by using an inducible P. aeruginosa strain. Induction was lower in biological fluids than in Mueller-Hinton broth.
Databáze: Supplemental Index