| Autor: |
Omura, S, Ikeda, H, Malpartida, F, Kieser, H M, Hopwood, D A |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; January 1986, Vol. 29 Issue: 1 p13-19, 7p |
| Abstrakt: |
Hybrid antibiotics mederrhodins A and B were produced by a recombinant strain consisting of the medermycin-producing Streptomyces sp. strain AM7161 containing part of the gene clusters for actinorhodin biosynthesis of Streptomyces coelicolor A3(2). Mederrhodin A has a hydroxyl group at the C-6 position of the medermycin molecule, and mederrhodin B is dihydromederrhodin A. The antimicrobial activity of mederrhodin A resembled that of medermycin. Mederrhodin B was almost devoid of antimicrobial activity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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