Recovery of norfloxacin in feces after administration of a single oral dose to human volunteers

Autor: Cofsky, R D, duBouchet, L, Landesman, S H
Zdroj: Antimicrobial Agents and Chemotherapy; July 1984, Vol. 26 Issue: 1 p110-111, 2p
Abstrakt: Twelve healthy volunteers received single 400-mg oral doses of norfloxacin. During the ensuing 48 h, from 8.3 to 53.3% (mean, 28%) of this dose was recovered in the feces. Peak drug concentrations in fecal specimens ranged from 207 to 2,716 micrograms/g.
Databáze: Supplemental Index