Efficacy of acyclovir against mouse cytomegalovirus in vivo

Autor: Wingard, J R, Bender, W J, Saral, R, Burns, W H
Zdroj: Antimicrobial Agents and Chemotherapy; August 1981, Vol. 20 Issue: 2 p275-278, 4p
Abstrakt: Acyclovir reduced mortality and organ virus titers in mice inoculated intraperitoneally with 10 50% lethal doses of mouse cytomegalovirus. This susceptibility to acyclovir of a herpesvirus which lacks thymidine kinase is surprising. Alternative phosphorylating enzymes may account for this susceptibility.
Databáze: Supplemental Index