Autor: |
Kuhrt, Michael F., Fancher, Marilyn J., Jasty, Venkatanarayana, Pancic, Francis, Came, Paul E. |
Zdroj: |
Antimicrobial Agents and Chemotherapy; June 1979, Vol. 15 Issue: 6 p813-819, 7p |
Abstrakt: |
Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be partially reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone. |
Databáze: |
Supplemental Index |
Externí odkaz: |
|