| Autor: |
Horodniceanu, Thea, Bouanchaud, D. H., Bieth, G., Chabbert, Y. A. |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; November 1976, Vol. 10 Issue: 5 p795-801, 7p |
| Abstrakt: |
Two plasmids determining resistance to tetracycline (RIP500) and to chloramphenicol, erythromycin, lincomycin, and pristinamycin I (RIP501) were isolated from a strain of Streptococcus agalactiae. The frequency-of-resistance loss is very low for RIP500 (<3 × 104) but higher for RIP501 (the efficiency was dependent upon the curing agents and incubation temperature and varied between 0.5 and 96%). Derivatives susceptible to all drugs were also obtained. RIP500 and RIP501 have similar molecular weights (17.9 × 106and 20 × 106, respectively) and represent different percentages of total deoxyribonucleic acid (0.4 and 4%, respectively). The number of copies of RIP500 and RIP501 per cell is different, and these plasmids are likely replicated under different kinds of control (stringent and/or relaxed). No plasmid deoxyribonucleic acid was found in a derivative of strain B96 susceptible to all drugs. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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