Double-Blind Comparison of Phlebitis Produced by Cefazolin Versus Cephalothin

Autor: Shemonsky, Natalie K., Carrizosa, Jaime, Kaye, Donald, Levison, Matthew E.
Zdroj: Antimicrobial Agents and Chemotherapy; April 1975, Vol. 7 Issue: 4 p481-482, 2p
Abstrakt: In a double-blind study with each patient as his own control, 1 g of cefazolin and 2 g of cephalothin were administered intravenously every 6 h to 20 patients in opposite arms for a period of 48 h each. The degree of phlebitis was significantly more severe with cephalothin than with cefazolin (P< 0.05); however, neither the incidence of phlebitis nor the time of onset of phlebitis was significantly different between the two drugs.
Databáze: Supplemental Index