| Autor: |
Borders, D. B., Kirby, J. P., Wetzel, E. R., Davies, M. C., Hausmann, W. K. |
| Zdroj: |
Antimicrobial Agents and Chemotherapy; May 1972, Vol. 1 Issue: 5 p403-407, 5p |
| Abstrakt: |
An analytical procedure was devised which can distinguish members of the streptothricin family of antibiotics. It is based upon an analysis of the hydrolysis products of the antibiotics using a Technicon amino acid autoanalyzer under special conditions. The various fragments including the different streptolidine-amino sugar compounds were well resolved. A basic water-soluble antibiotic discovered in our laboratories and named LL-BL136 was compared to other members of this group by this technique. It was not differentiated from the antibiotic SF-701 reported by Tsuruoka. The autoanalyzer results along with other physicochemical data permitted a structure proposal for this antibiotic, which is the N-methyl-desformimino derivative of antibiotic LL-AC541. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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