Autor: |
Elings, Wouter, Chikunova, Aleksandra, van Zanten, Danny B., Drenth, Ralphe, Ahmad, Misbha Ud Din, Blok, Anneloes J., Timmer, Monika, Perrakis, Anastassis, Ubbink, Marcellus |
Zdroj: |
Antimicrobial Agents and Chemotherapy; July 2021, Vol. 65 Issue: 8 |
Abstrakt: |
The β-lactamase of Mycobacterium tuberculosis, BlaC, is susceptible to inhibition by clavulanic acid. The ability of this enzyme to escape inhibition through mutation was probed using error-prone PCR combined with functional screening in Escherichia coli. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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