Autor: |
Frey, Daniel, Machler, Marco, Seger, Reinhard, Schmid, Werner, Orkin, Stuart H. |
Zdroj: |
Blood; January 1988, Vol. 71 Issue: 1 p252-255, 4p |
Abstrakt: |
In a patient suffering from X-linked chronic granulomatous disease (X-CGD)—a disorder of phagocytesuperoxide gen-eration—and McLeod syndrome, characterized by the absence of the red cell Kell antigen, we identified a deletion of the entire X-CGD gene by means of DNA hybridization with a cDNA probe. Our findings suggest that the X-CGD and McLeod loci are physically close in the p21 region of the X chromosome proximal to the Duchenne muscular dystrophy locus.© 1988 by Grune & Stratton, Inc. 0006-4971/88/710l-0048$ 3.00/0 |
Databáze: |
Supplemental Index |
Externí odkaz: |
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