| Autor: |
Lamon, Joel M., Frykholm, Bruce C., Tschudy, Donald P. |
| Zdroj: |
Blood; May 1979, Vol. 53 Issue: 5 p1007-1011, 5p |
| Abstrakt: |
Lead poisoning and acute intermittent porphyria (AIP) may exhibit similar neurologic manifestations, and they have in common elevated excretion of urinary aminolevulinic acid (ALA). Despite their similarities, the possible pathophysiologic connection between AIP and lead poisoning is not known. Because intravenous hematin administration has produced bio- chemical improvement in AIP, a hematin trial in lead intoxication was of interest with respect to some of the heme metabolism abnormalities observed in that condition. Significant diminution of urinary ALA and coproporphyrin excretion occurred in association with intravenous hematin administration. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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