Long-Lasting HHV-6 Reactivation and Immune Recovery In Adult Long-Survivors After Umbilical Cord Blood (UCB) Allo-SCT: A Comparison With PBSC As Stem-Cell Source

Autor: Illiaquer, Marina, Malard, Florent, Guillaume, Thierry, Imbert-Marcille, Berthe-Marie, Delaunay, Jacques, Le Bourgeois, Amandine, Rimbert, Marie, Bressollette-Bodin, Céline, Precupanu, Cristina, Peterlin, Pierre, Moreau, Philippe, Mohty, Mohamad, Chevallier, Patrice
Zdroj: Blood; November 2013, Vol. 122 Issue: 21 p2065-2065, 1p
Abstrakt: HHV-6 reactivation and HHV-6 encephalitis have been identified as significant complications in the post allo-SCT setting, especially in patients receiving UCB as the stem cell source (Scheurer et al, BMT, 2012). It is known that HHV-6 reactivations occur mainly within the first month post-transplant and may persist few months after allo-SCT (Chevallier et al, BMT, 2010). At our knowledge, no study has evaluated the long-term persistence of HHV-6 infection and its consequences in patients after allo-SCT.
Databáze: Supplemental Index