| Autor: |
Chen, Tumei, Wang, Chenchen, Hu, Linlin, Lu, Hao, Song, Fangyu, Zhang, Anding, Wang, Xiangru, Chen, Huanchun, Tan, Chen |
| Zdroj: |
Future Microbiology; July 2021, Vol. 16 Issue: 10 p721-729, 9p |
| Abstrakt: |
Aim:This study aims to develop a subunit vaccine with high cross-protection for Streptococcus suis. Materials & methods:Four-week-old female BALB/c mice were first immunized with a single and mixed protein. Various indicators, such as antibody titers and various cytokine levels, were further analyzed. Results:The results showed that purified recombinant proteins IF-2 and 1022 had a good protective effect against lethal doses of S. suisserotype 2 and S. suisserotype 9. This study showed immunization with recombinant proteins. Conclusion:IF-2 and 1022 can enhance cross-protection against S. suisserotypes 2 and 9. |
| Databáze: |
Supplemental Index |
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