Autor: |
Stahelin, Hannes B., Winchell, H.S., Kusubov, N. |
Zdroj: |
Blood; January 1970, Vol. 35 Issue: 1 p86-89, 4p |
Abstrakt: |
Three human subjects with folic acid and one with vitamin B12deficiency failed to show any effect of ingestion of L-methionine (400-800 µg./kg. body weight) on the production of 14CO2from parenterally administered high specific activity L-histidine (imidazole-2-14C). It is suggested that the inhibitory effect of methionine on intestinal absorption and cell membrane transport of histidine can explain previously published effects of methionine on the oxidation of the imidazole-2 carbon atom of L-histidine and that a direct effect of methionine on histidine metabolism need not be invoked. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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